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Domestic air cleaners improve heart health for COPD patients

A six-month study led by Johns Hopkins Medicine has found that portable home air purifiers improve some cardiovascular health markers in those suffering from chronic obstructive pulmonary disease.

Also known as COPD, the illness is often defined by chest tightness, shortness of breath, and a chronic cough, with arrhythmias, heart failure, heart attack, and strokes commonly accompanying the condition, leading to one of the biggest causes of death globally. 

selective focus photography of anatomy lungs

A secondary study to the larger Clean Air Study, the new work has found that portable air purifiers, when used indoors, can improve the debilitating and potentially deadly symptoms associated with COPD. In total, 85 men and women from the wider research project, all of who were aged 65 and over and diagnosed with COPD, participated in this latest undertaking. 

‘We’ve seen that air pollution in the home, where people spend the majority of their time, contributes to impairments in respiratory health. We hypothesised this pollution is a big driver of cardiovascular disease and cardiac events in people with COPD,’ said lead author Sarath Raju, M.D., M.P.H., and assistant professor of medicine specialising in obstructive lung disease at the Johns Hopkins University School of Medicine. 

In order to test the theory, trained technicians took air samples of indoor particulate matter of varying sizes from the homes of participants. Then, 46 randomised people were given two portable air cleaners with HEPA and carbon filters for use at home. The remainder of the group were given placebo cleaners capable of circulating air but with filters removed.

Indicators of lung health were then measured and tracked at one week, three months and six months using standard clinical tests including blood pressure and heart ultrasounds. Heart rate monitors were also worn 24-hours a day during each testing period. At the end of the study, it was found all 46 participants using the active filters showed improved health markers, including a 25% increase in heart rate variability (HRV). Those using cleaners with no working filter did not display any improvements.

HRV is a common measure of heart health as a healthy heart is constantly adjusting its rate to meet the physical needs of the body. 20 participants using working cleaners also exhibited a 105.7% increase in root mean square of successive differences between normal heartbeats, another key sign of fitness. In addition, researchers uncovered a correlation between increased ultra fine particles and poor heart health markers, including variability, concluding that more work is needed in this area. 

‘Ultrafine particles might be the most potent particles in terms of health consequences,’ said study author Meredith McCormack, M.D., M.H.S., and associate professor of medicine at the Johns Hopkins University School of Medicine and director of the BREATHE Center (Bridging Research, Lung Health and the Environment). ‘These particles and other indoor air pollutants can cause systemic inflammation in susceptible patients like those with COPD. Our study shows there’s a negative impact on cardiovascular health, as well.’ 

You can read the full study here, and find out more about why indoor air quality is an issue that must be addressed urgently here.

Image: Robina Weermeijer

 

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